Saturday, August 31, 2019

Case Study of Time-Critical Management Essay

Based on the EMV done above, the optimum decision strategy based on the cost alone is to get the component from ARC solution and transport it via Land route. Consider the calculations attached in Memo 1 to draw the conclusion in the above analysis Sensitivity Analysis Resale of new thrust reverser . Considering the ‘Y’ as the number of years after which we are able to sell the newly purchased Thrust Reverser (Node B). As seen from Memo 2, the optimum decision strategy remains the same as long as ‘Y’ is equal or more than 2 years. Probability of whether BCS component is fit or not Consider the probability that the BCS component will fit is ‘p’ and then the probability that BCS component will not fit is (1-p) As seen from calculation done from Memo 3, The optimum decision strategy remains the same as long as p < 51.7 %. Since its mention that the probability that BCS component fits is 35% to 50%, the optimum decision remains the same. Based on the sensitivity analysis done above, our optimum decision strategy doesn’t change unless the variables take unreasonable values. However this optimum decision strategy is calculated based on cost alone, If we consider the reputation loss along with revenue for the Latin Airlines, then transporting the ARS solution component by land has a 20% chance of delaying the aircraft by 3 more days leading to significant loss in reputation of the Airlines. Whereas transporting the ARS solution component by Air doesn’t have such of extending the delay and is 100% safe way of transport. Considering the difference in the cost between transferring ARS solution component by Air and by Land, the cost difference is only $7659, which is very negligible. So after considering the loss in revenue along with reputation for the Latin airlines, we suggest that the Optimum decision strategy will be to get the component from ARC solution and transport it via Air route.

Friday, August 30, 2019

Entertainment Is Something Which Distracts Our Daily Life Routine Essay

What is entertainment? There are many definitions of entertainment but I look at it as something which diverts or may distract us from our daily life routine. It helps us relax for periods of time thus forget our worries and cares; our habits and thoughts are interrupted, it rests our minds and nerves, though it can also drain our energies thus exhaust our bodies (Herbert, 2012). There are multiple forms of entertainment that are in play nowadays that people find a good way to release themselves from the daily life routines. Entertainment has many forms that are endless but the main agenda is to divulge us from the daily patterns of life .In the resent generation people have been looking for better and easier ways to forge a living in a simpler manner, therefore making recreation or entertainment the most available solution to releasing them from never-ending stress and responsibilities in their daily lives (Herbert, 1946). Entertainment diverts our thoughts to moments of laxity and less care to our worries and anxieties. Our worries can either bring our heart and mind to a low or bring us to a high, in a sense that it brings an immeasurable amount of adrenaline or a low to mean laxity of mind and less activity of body. And this immense adrenaline definitely is brought about by sporting activities. Sporting activities make most of the body parts to actively participate therefore making us have the feeling of our existence within. Again in the present times technology has greatly evolved forcing humans to evolve with it. With this aspect involved, we are now encircled by smart phones, internet and all kinds of similar gadgets like television sets and iPods which have a considerable amount of our daily working life and entertainment of which we can’t imagine our entertainment or leisure time without. Everything that we are involved with at this age in time is all about entertainment as Tony Robbins puts it (Herbert, 2012) . Reading and writing has been a form of entertainment for many people. This is by books, magazines, blogs reading and writing in internet or paper. To the children reading of comics of heroes like Bat man, Super man and many others makes the happy and entertained. Also children as opposed to the adults who write; they find it entertaining to draw patterns and characters on paper. All this is educative and entertaining at the same time because it moves us from daily patterns of life while we are adding knowledge. Marshall McLuhan say that anyone who tries to make a distinction between education and entertainment doesn’t know a thing about either dance; music and films have found their way into people’s definition of entertainment and recreation (Herbert, 1946). A huge number of entertainment gadgets presently have to have music or visual images to be considered as items of entertainment. This is the other good way that recreation time can be well utilized. This is found in social joint like pubs, bars, disco etc. From my perception, our personalities can be defined by how we choose our entertainment activities e.g. If you are into parachuting you might be quite crazy, courageous and also an energetic person. But one who spends hours drawing, he or she might be a shy person, maybe calm and may also you be a patient person. Some entertainment forms may prove illogical e.g. ten people chasing after one ball but all in all each of us is unique in his or her own way thus we have what we like more us compared to other things. In conclusion entertainment does distract us from daily life routine because it soothes our feelings thus making us happy for we create our own worlds and forget about the rest of the world. Different entertainment activities create a longer period of happiness in turn causing continuous distraction.

Thursday, August 29, 2019

Gen Chem Study Guide

A. WORK-OUT PROBLEMS: Write formulas for the following: calcium nitratephosphorous pentafluoride aluminum carbonatestrontium hydroxide methanepotassium oxide lithium chloridebarium sulfate phosphate iondinitrogen tetroxide Give the complete electron configurations of: S, O2-, and Mn. For the following molecules/ions, give the Lewis structure, molecular geometry, and electron pair geometry: NO2-SF4 Write Lewis structures to represent all resonance forms of CO32-. 5. How many joules of heat energy are lost when a 100-gram sample of a metal (with a specific heat of 0. 312 J/(g?C) cools from 80. 0? C to 30. 0? C? Calculate the number of moles in: 4. 20 X 1024 molecules of SO2 240 grams of NaOH 5. 00 liters of H2 gas at 0? C and 1. 00 atm. 1. 7 liters of Ar gas at STP 7. How many grams of AlCl3 can be prepared from 50. 0 g of Al and 100. 0 g of Cl2 according to the equation: 2 Al + 3 Cl2 ? 2 AlCl3 ? How many neutrons are there in 131I? Which bond is the most polar? I-ClI-Br I-SI-I Circle the molecules that are polar (have a dipole moment): CCl4CH4H2ONH3HBrCHCl3 CCl2F2 How many unpaired electrons does the Si atom have?Write the correct Lewis structure for CS2. Write the formal charges on each atom in [F-S=F]2+ (lone pairs are not shown). How many ions are formed when Ca3(PO4)2 dissolves? How many protons, neutrons, and electrons are there in 19F- ion? Discuss the properties of molecules used as liquid crystals. (ignore this question) What is the molarity of the solution made when 1. 25 grams of sodium chloride are dissolved in 500 mL of water? What is the hybridization of the carbon atom C2H2 ? What is the molecular formula of a compound with 30. 5% N and 69. 5% S, and it has a molar mass of 184 g/mol?How many electrons are found at the sublevel 1=2? How many sigma and how many pi bonds does carbon dioxide have? How many milliliters of 2. 5M solution are needed to prepare 500 mL of 0. 08M solution? How many milliliters of 1. 25M hydrochloric acid are needed to neutra lize 50. 0 millimeters of 0. 55M barium hydroxide? The vapor pressure of SiCl4 is 100 mmHg at 5. 4? C and the normal boiling point is 56. 8? C. What is ? Hvap for SiCl4 in kJ/mol? B. MULTIPLE CHOICE A 34. 6 g sample of calcium oxide is a. 0. 0346 molb. 0. 617 molc. 1. 23 mold. 34. 6 mol 2.When the following equation is balanced, the total number of nitrogen atoms on the reactant side is:BaCl2(aq) + AgNO3(aq) ? Ba(NO3)2(aq) + AgCl(s) a. 2b. 3c. 4d. 6 Given that 4 HNO3(aq)? 4NO2(aq) + 2 H2O(l) + O2(g), the amount of NO2 which could be produced from 3. 00 mol HNO3 is: a. 138 gb. 177 gc. 184 g d. 236 g Given that 3 CuCl2(aq) + 2 Al(s) ? 3 Cu(s) + 2 AlCl3(aq), the amount of Al required to produce 42. 4 g of Cu is: a. 12. 0 gb. 28. 3g c. 40. 5 gd. 42. 4 g The type of substance least likely to appear as a product in a net ionic equation is a soluble saltc. weak electrolyte an insoluble saltd. an insoluble gas When a solution of NiBr2 is mixed with a solution of (NH4)2CO3 the net ionic equa tion is: a. NiBr2(aq) + (NH4)2CO3(aq) ? NiCO3(s) + 2 NH4Br(aq) b. Ni2+ (aq) + 2Br- (aq) ? 2 NH4+ (aq) + CO32- (aq)? NiCO3(s) + 2 NH4+ (aq) + 2 Br- (aq) c. Ni2+ (aq) + CO32-(aq) ? NiCO3(s) d. Br-(aq) + NH4+ (aq) ? NH4Br(aq) When a sample of chlorine gas at 35? C doubles in volume, its pressure stays the samec. is half as great doubles d. increases fourfold A 385-mL sample of oxygen gas collected at 747 mm Hg and 27. 4?C would occupy what volume at STP? a. 344 mLb. 356 mLc. 416 mLd. 431 mL A 9. 74 g sample of CO2 will occupy 6. 37 L at 0. 829 atm only if the temperature is a. 17. 6? Cb. 6. 61? Cc. 564? C d. above 100? C A sample of N2 would obey the ideal gas law most closely at 0. 68 atm and –68? Cc. 680 atm and –68? C 0. 68 atm and 680? Cd. 680 atm and 680? C A 50. 0 g sample of an unknown substance absorbed 1. 64 kJ as its temperature changed from 36? C to 98? C. The specific heat of the unknown is: a. 0. 53 J/(g? C)b. 0. 76 kJ/(g? C)c. 1. 3 kJ/(g? C)d. 1. 9 kJ/(g?C) The formation reaction in this list is a. Sn(s) + 2Cl2(g) ? SnCl4(l)c. 2C2H5OH(l) + 7O2(g) ? 4CO2(g) + 6H2O(l) b. 2HNO2(l) + NO(g) ? 3NO2(g) + H2O(l) d. 2Cl2O(g)? 2Cl2(g) + O2(g) For CH4(g) + 4Cl2(g) ? CCl4(g) + 4HCl(g), ? H? =-402 kJ. How much HCl was formed when 201 kJ were given off? a. 18. 2 gb. 72. 9 gc. 146 gd. 292 g Use the thermochemical equations below to calculate the enthalpy of reaction for NOCl(g) + Cl(g) ? NO(g) + Cl2(g) N2(g) + O2(g) + Cl2(g) ? 2NOCl(g)? H? =105. 2 kJ N2(g) + O2(g) ? 2NO(g)? H? =180. 7 kJ Cl2(g) ? 2Cl(g)?H? =243. 2 kJ a. 529. 1 kJb. 264. 6 kJc. -83. 85 kJd. –167. 7 kJ The energy of a photon of electromagnetic radiation is directly proportional to its a. speed in a vacuum c. frequency b. wavelength d. diffraction The volume in space where an electron with a particular energy is likely to be found is called a wave functionc. the spin quantum number a photond. an orbital The frequency of a microwave with a wavelength of 12. 2 cm is a. 8. 08 x 10-3 3 Hzc. 2. 46 x 107 Hz b. 3. 66 x 109 Hzd. 2. 46 x 109 Hz The number of orbitals in the 4p subshell is a. 1b. 3c. 5d. 18The energy difference between the two energy levels responsible for the 451 nm blue-violet line the emission of indium is a. 6. 65 x 105 Jc. 2. 27 x 1018 J b. 1. 50 x 105 Jd. 4. 40 x 10-19 J The maximum number of electrons contained in a 3d subshell is a. 2b. 6c. 10d. 18 The number of valence electrons shown in the Lewis formula for SF4 is a. 40b. 34c. 32d. 5 The formal charge on O in the compound H2O2 (in the order HOOH) is a. 0b. –2c. –1d. –3 The resonance structures for SO2 include each of these except a. O=S-Ob. O-S=Oc. O=S=Od. S-O=O The O-S-O bond angle in SO2 is closest to a. 0? b. 109. 5? c. 120? d. 180? Of the following substances, the least polar bonds are those found in a. H2b. H2Oc. H2Sd. CH4 Matter is said to be transparent to those wavelengths it a. absorbs b. diffractsc. cyclesd. transmits In formaldehyde (H2CO) the electron pairs are located about the central atom in which type of arrangement? a. pyramidal b. tetrahedralc. trigonal planard. bent The molecular geometry of SO3 is best described as a. linearb. trigonal planarc. tetrahedrald. bent The molecular geometry of CO32- is best described as a. linearb. trigonal planerc. tetrahedrald. bentOf the following, which has a molecular geometry that is not planar? a. CH4b. H2COc. C2H4d. SO3 When a solution of sodium chloride and a solution of lithium nitrate are mixed a precipitate forms a new salt is formed a gas is evolved no reaction occurs When solutions of barium chloride and sodium sulfate are mixed, the spectator ions in the resulting reaction are a. only Ba2+b. only SO42-c. Only Na+d. both Na+ and Cl- Which of the following ionic compounds is insoluble in water? a. NH4Clb. AgNO3c. KId. Na2S Given that Fe2O3(s) + 3CO(g) ? 2Fe(s) + 3CO2(g), when 45. 3 g of CO reacts quantitatively with 79. g of Fe2O3, the amount of Fe formed is a. 45. 3 gb. 55. 8 gc. 60. 2 gd. 79. 8 g For the above reaction, when 45. 3 g of CO reacts quantitatively with 79. 8 g of Fe2O3, the amount of leftover reactant is a. 34. 5 gb. 24. 0 gc. 17. 8 gd. 3. 2 g 36. The oxidation numbers of P, S and Cl in H2PO2-, H2S and KClO4 are, respectively a) -1, -1, +3 b) +1, -2, +7 c) +1, +2, +7 d) -1, -2, +7 e) -1, -2, +3 37. Identify the oxidizing agent in the following redox reaction. Hg2+(aq) + Cu(s) > Cu2+(aq) + Hg(l) a) Hg2+(aq) b) Cu(s) c) Cu2+(aq) d) Hg(l) e) Hg2+(aq) and Cu2+(aq)

Wednesday, August 28, 2019

Faith Healing and the government should it be protected or monitored Dissertation

Faith Healing and the government should it be protected or monitored - Dissertation Example (1)Is refusal of medical treatment to children due to parents’ religious beliefs a valid and legitimate decision? (2) Can faith healing be considered as viable medical approach? To clarify further these questions the following sub-questions are addressed: Is the practice of faith healing a religious right? Should faith healing be protected by the state? Is faith healing, as practice, be considered as child abuse and first-degree murder when parents avoid using western medicine on a treatable illness and their child eventually dies? Is faith healing similar with placebo effect? The research used qualitative research for its research methodology and employed documentary analysis, group discussion, and reflection journal for its method. Some of the findings of the research are: (1) Religious belief and faith healing are the same even if the two concepts are closely connected. (2) Faith healing is not a viable form of health care service. (3) There is need to clarify further the n otion of religious belief, since, there is ambivalence in its understanding. This ambivalence affects Court decisions regarding parental decisions refusing medical treatment for their child. Table of Contents Chapter 1 Introduction 5 1.1.Background of the Study 6 1.2. Research Questions 8 1.3. Objective and Aims of the Research 10 1.4. Significance of the Study 11 1.5.Assumptions of the Study 11 1.6. Theoretical Framework 12 1.7. Definition of Terms 13 1.8.Structure of the Dissertation 15 Chapter 2 On Religious Beliefs and Refusal of Medical Treatments 16 2.1. Introduction 16 2.2. Religious Beliefs: A Search for its Meaning 18 2.2.1. A View of Religion 19 2.2.2. On the Idea of God: A Very Brief Elucidation 26 2.2.3. Spirituality 28 2.2.4. On Religious Beliefs: An Attempt to Definition 31 2.3.1. Parental Decision and Religious Belief: Parental Control 34 2.3.2. Free Exercise Clause: Parental Decision and Refusal for Medical Treatment 36 2.3.4. On the Other Side: The State and Parens Patria 38 2.3.4.1. The Clash: The British Approach 40 2.3.4.2. The Clash: The American Approach 41 2.4. Some Observations 42 Summary 43 Chapter 3 On Faith Healing 44 3.1. Introduction 44 3.2. Faith Healing: A Brief History and Its Definition 46 3.2.1. Faith Healing: Its Definition 48 3.3 Faith Healing and the State 50 3.4. Faith Healing and Placebo Effect 51 Summary 53 Chapter 4 Research Methodology 54 4.1.Introduction 54 4.2. Research Design 54 4.3. Research Methodology 56 4.4. Research Approach 57 4.5. Method of Data Collection 57 4.6. Ethical Consideration 60 Chapter 5 Findings and Discussion 63 5.1. Introduction 63 5.2. The Findings 63 5.2.1. A Conceptual Understanding of Religious Belief 64 5.2.1.1. Religious Beliefs, Validity, and Decision-Making 65 5.2.1.2. Religious Beliefs, Decision, and Legitimacy 66 5.2. Faith Healing: A Healing Alternative? 67 5.2.1. Faith Healing: Alternative Health Care 68 5.2.2. Faith healing and Placebo 69 5.3. Discussion 70 Summary 73 Chapter 6 Conc lusion and Recommendation 74 6.1. Conclusion 74 6.2. Recommendations 76 References 77 List of Figure Figure 1 p. 12 Figure 2 p. 25 Figure 3 p. 29 Figure 4 p. 31 Figure 5 p. 55

Flat U.S. Wages Help Fuel Rebound in Manufacturing Assignment

Flat U.S. Wages Help Fuel Rebound in Manufacturing - Assignment Example With the sluggish economy, waning consumer confidence, and less access to credit (among other factors), manufacturers have struggled to keep pace. This reality, however, appears to be drawing to a close as manufacturing numbers and production output have been up in recent quarters. This phenomenon is partly fueled by the reality that wages in this sector have remained stagnant, ironically allowing manufacturing companies to catch up on their productivity and increase profitability due to less expense related to labor costs and benefits. It is important to understand the relationship that exists between labor cost and the cost of manufactured goods. In times of decreased production, if wages kept pace with inflation, many plants would quickly find themselves in dire situations. With the tables reversed, however, and production picking up due to stagnant wages, many industries in the manufacturing sector are returning to the United States. This further fueling the economic development, even though many argue that the retailing and services side of the economy are left out in the dark because of decreased buying power exhibited by workers. There are certainly challenges facing the manufacturing industry in America as it continues to compete in an increasingly global economy, but the current signs are positive and the trends are moving in the right direction.

Tuesday, August 27, 2019

Literature Review on Domestic Abuse From 5 different articles from Dissertation

Literature Review on Domestic Abuse From 5 different articles from Columbia College - Dissertation Example It has often been observed to lead towards permanent physical damages as well as disability of the victims. Children are also classified to be affected due to domestic violence acts which certainly influence their growth as well as social development in a healthy and prosperous way. Article 1 Annotated Bibliography Reference Citation Certain, H. E., Mueller, M., Jagodzinski, T., & Fleming, M. (2008). Domestic Abuse During the Previous Year in a Sample of Postpartum Women. JOGNN 37(1), pp. 35-41. What is the article about? The article relates to domestic abuse of postpartum women. Information about sample and population The sample size considered for the research in this article concentrated on one 1,519 women who were visiting for a postpartum appointment in clinics located in rural, urban as well as suburban locations. Stating precisely, women who were18 years of age and older, being seen for a postpartum visit at 35 obstetric and gynecologic clinics located in 15 Wisconsin counties of United States, were the participants of this study. . Article summary The article is related to the domestic abuse witnessed by postpartum women. The women who visited the clinic were examined through a routine screen to find out whether they have faced any emotional or physical abuse. Why was the research performed? The research was performed to identify the frequency of women being victimized to domestic abuse or violence within the research area. The study also intended to reveal the consequences led by the outcomes of domestic abuse like mental illness, physical damages as well as disability. Findings Following a cross-sectional survey, the study reveals that 112 women were suffering of domestic abuse which provided an alarming ratio of 1 in every 14 women as the victim. It was further revealed that domestic abuse results in poorer health as well as depression amid women. Strengths The article helps in understanding the consequences as well as identifies the elements linked up with domestic abuse. Weaknesses The findings of the article were observed to lack in terms of consistency as well as there was no typical profile of abused women during pregnancy. Implications for Practice The implications of the findings obtained in the study suggest that policies need to be formulated for better identification of domestic abuse. Literature Review According to Certain, Mueller, Jagodzinski and Fleming (2008), 112 women were reported to be a victim of abuse out of the total respondents, i.e. 1,519 women who required postpartum treatments. The study also revealed that abuse of women can result to chronic poor physical health issues, chronic mental illness as well as preterm labor along with low birth weight infants. The clinics providing prenatal as well as postpartum care are thus required to be aware as well as take special care of victims suffering from domestic violence. Postpartum depression has been considered with great significant in this article. The find ings of this study further suggest that depressions as well as mental stresses are also associated with domestic abuse, which further increases the severity of such conducts. The interconnection among domestic abuse as well as postpartum depression is less recognized. However, in few studies which were conducted found out the relation among the postpartum depression as well as domestic abuse. Hispanic ethnicity was considered to be associated with domestic abuse in this study. For instance, the study reveal

Monday, August 26, 2019

In a culturally diverse word, the universality of human rights remains Assignment - 1

In a culturally diverse word, the universality of human rights remains unsettled. Discuss - Assignment Example All people should not be denied their rights unless in a situation that demands legal action against them. For example, the right to liberty can be withdrawn when a person becomes guilty and gets convicted of an offence. International human rights law in the form of treaties, international law, general principles, and other international law sources are factors that determine Human rights. International law seeks to achieve the universality of human rights; however, it faces challenges resulting from the current cultural diversity. Culture is the people’s way of life and contributes much to aspects of their lives. The different cultures that exist in the world are a challenge to trying to implement human rights law. Some cultures would not allow some actions as they differ with them. This work seeks to discuss how the diverse culture in the world contributes to the efforts put towards achieving or settling universality of human rights. It will discuss how the culture relates t o human rights and how it contributes either negatively or positively towards achieving the universality of human rights. It will also focus on different organizations formed to protect and educate the public on understanding their culture and human rights, and how their progress is at present. Background Information Although there have been developments in evolution of human rights, the process is under serious challenge. From 1945, more development of international human rights standards has occurred as compared to previous years (Forsythe, 2009: xviii). However, international issues like Chinese development as a world power, and the United States’ efforts to maintain national security after the September 2001 attack challenge these developments on human rights. As much as the international community talks of human rights and rights laws, there is a violation of the rights as a result of these developments. People did not know about human rights until 1945, but the United S tates and France practiced ‘rights of man’ although no human rights treaties existed until the period of United Nations. The treaties that existed were rights of foreigners. According to Forsythe, it is D. Roosevelt and others who pushed for inclusion of human rights in the United Nations charter. They believed that human rights contributed to international security and peace and that it was human rights’ violation that led to the origin of World War II (Forsythe, 2009: xviii). The quest to adoption of human rights to the UN charter became the origin of their development. Universality of Human Rights Universality is the quality of being dominant or available. Human rights universality is thus the ability to the existence of human rights to every human being. Universality is rather the ability of a society or state to allow its citizens to enjoy the availability of human rights. The diversity in culture, in the present world, affects the universality of human righ ts in various ways. Different cultures affect how their citizens enjoy the provision of human rights. According to Osiatyn?ski, the African take on human rights was not on an individual basis; it focused on the community. This is an indication that culture has a relative impact on human rights universality. In most tribes, in Africa, for example, the decision to marry does not come from a girl, but it is a decision made by the family and clan or the community, depending on the family status (Osiatyn?ski, 2009:128). This practice

Sunday, August 25, 2019

British Airways- Case Study Essay Example | Topics and Well Written Essays - 1500 words

British Airways- Case Study - Essay Example ifically, it seems that the poor communication among the employees of the firm has been a constraint towards the development of the firm’s profitability. This problem has led to the design and application of inappropriate rules that govern the firm’s structure and its communication with the customers. It is also because of this fact that employees do not perform in accordance with the goals set by the firm’s management and as a result the financial development of the company faces severe delays. The poor communication among the employees in British Airways can be assumed through a series of facts related with the firm’s daily operational activities as well as the performance of its leaders since the firm’s entrance in the British market (in 1974). More specifically, immediately after the firm’s formation in 1974 from the merge of British Overseas Airways Corporation (BOAC) and the British European Airways (BEA) the employees of the two companies (who now should cooperate) were differentiated regarding their cultural aspects. In this context, the former employees of BOAC believed to belong in a ‘traditional’ and ‘high class’ firm different from the ‘low class’ BEA. On the other hand, the employees in BEA also considered employees of BOAC to be snob while they saw themselves as ‘true competitors’ in the British market. For this reason, it can be assumed that for employees in BEA the merger with BOAC was a wrong decision which could lead the new formed company, the British Airways, in severe financial losses. In accordance with the above the cultural differences among employees in British Airways were intensive since the firm’s formation and this fact has been the main reason for the lack of effective communication among employees in the firm’s particular departments – at least at the firm’s initial ‘steps’ in the British market. The above problem has been limited partially after the reduction of staff in 1981 by Lord King (the

Saturday, August 24, 2019

Using Ownership Incentives in China Case Study Example | Topics and Well Written Essays - 2500 words

Using Ownership Incentives in China - Case Study Example On the other hand, the method has also been seen to reduce employee turnovers in the organizations where it is practiced. The outcome of the study are of great significance to Ben Freed and his partners in their quest to export this management culture to China with the aim of expanding their business and market globally. Analysis of the various aspects that would impact on the company’s incentive ownership culture would significantly inform the choice of practice to be adopted by the company, hence acting proactively to avert potential risks on the same. On the other hand, the findings of the study are of significant importance to employees, especially the experts based in the US, who are expected to move into a different country to introduce the new management system. The knowledge gained is important in preparing them on what to expect from the new geographical and cultural setup. The local culture of ownership as practiced in the Silicon Valley could be exported to China in various ways. For instance, the mode of payment for the China-based employees, together with all other employee motivational practices done in the US, could be introduced for the Chinese employees. This would thus mean that the payment for these employees be inclusive of their normal salaries together with the stock ownership percentages as determined by their respective positions in the company (Dong, Bowles and Ho 826). With the use of employee ownership approach, the CEO is well placed in motivating the workers to be responsible and work hard considering that their own success is determined by the company’s success. Additionally, the use of this approach is important in demonstrating to the employees that the company values all stakeholders in it equally, and gives similar treatment to all its employees. As observed in the historical practices in China, however, there could be n umerous challenges in

Friday, August 23, 2019

BUS599 - Integrative Project, Mod 5 Case Assignment Essay

BUS599 - Integrative Project, Mod 5 Case Assignment - Essay Example One Balancing Loop Availability of new workers: This is an example of a balancing loop. In the food market, increasing new workers can be a limiting factor to the growth of the market. Explain each one of these loops - what are the causal factors and how do they affect each other. For the Reinforcing loop, you should look for an area where there is growth and for the Balancing loop, you need to look for goal behavior. Once you have identified and explained these critical feedback loops, you need to identify how Whole Foods Market has generated organizational learning, and how they can go further and generate additional organizational learning. What do they need to do to improve their performance further? Balancing Loop A balancing loop is a situation where a feedback reduces the effects of change in a system. It occurs when an action tries to bring two different things into an agreement or any other situation when one tries to provide a solution for a given problem, achieving a given goal etc. It can also be explained as what moves the systems in the direction of the equilibrium. A balancing loop is said to bring a negative feedback. Reinforcing Loop A reinforcing loop is a case where a feedback increases the effect of a change in a system. ... 20). Causal Factors and how they affect the Balancing and Reinforcing Loops Demand The reinforcing loop will either be determined by demand or by subsidy and all of these can affect the profitability of production of organic food. Whenever the farmers’ profitability is low, the other variables found in the reinforcing loop will automatically decrease and whenever the profitability is high, all the other will consequently increase. Subsidies are usually the biggest determinant in the market since market demand is still low and unreliable. Supply A big supply of raw materials reduces the market prices which will automatically decrease profitability for the whole food farmers, which will obviously discourage them. When there is a low supply, there will be high market prices and also the profitability will be high, a situation which will encourage the farmers to join the market. Market Price When there is a low supply of organic food, there will be a decrease in the demand for org anic food by retailers and this will result few purchases from the consumers. Also the raw material prices will act as a balancing factor by connecting to the price of organic food. The consumer price usually relies on the costs which are added in the whole food chain of distribution. Consumers The food consumers can only buy whole food when they find it to be appealing or attractive to them and this attractiveness of the whole food can be determined by several various factors like the price and the supply. Usually when the price is low and the supply is high coupled with diversity or variety of the organic food will definitely attract the consumers in large numbers. Equally when there is a high price and the supply is less the consumers will be discouraged from buying the organic

Thursday, August 22, 2019

Sleep and Rapid Eye Movement Essay Example for Free

Sleep and Rapid Eye Movement Essay Aw dreams that magical place that you drift off to in your sleep when everything goes just your way. Its that part of the day when everything is so pleasant and peaceful. Hello fellow classmates, and miss grubb today im here to talk about â€Å" Dreams† There are many things that make dreams happen. for example being in a good mood not being angry and getting a good nights sleep can make it happen. You can dream during(REM) rapid eye movement. What is rapid eye movement. Rapid eye movement (REM) is the stage of sleep characterized by rapid movements of the eyes. REM sleep typically occupies 20–25% of total sleep, about 90–120 minutes of a nights sleep. REM sleep is considered the deepest stage of sleep, and normally occurs close to morning. During a night of sleep, one usually experiences about four or five periods of REM sleep; they are quite short at the beginning of the night and longer toward the end. Many animals and some people tend to wake, or experience a period of very light sleep, for a short time immediately after a bout of REM. The relative amount of REM sleep varies considerably with age. A newborn baby spends more than 80% of total sleep time in REM. now lets talk about dreams themself. The human brain is responsible for many complex creations, but it can’t invent the image of people. So the â€Å"strangers† that you meet in your dreams actually have the faces of people who you’ve once seen in your real life but forgotten, like your childhood mailman or that guy you bumped into on the sidewalk that one time. Chances are that you’ve laid your eyes on more than a few individuals, and so the brain now has a huge cast of characters to play with when you drift off to sleep. Except for, in the case of extreme psychological disorder, every human being dreams. In fact, in a recent study, students who were awakened at the beginning of each dream but still allowed 8 hours of sleep, all experienced difficulty concentrating, irritability, hallucinations, and signs of psychosis in a span of three days. When they were allowed their REM sleep, their brains compensated for the lost time by increasing the percentage of the sleep spent in the REM stage. Dreams are a window into the subconscious. Even though most of the time, they’re completely random, disorganized, and we forget 90% of them within 10 minutes of waking up; many people have drawn inspiration from their dreams.

Wednesday, August 21, 2019

Chaucers Prologue To The Canterbury Tales Essay Example for Free

Chaucers Prologue To The Canterbury Tales Essay Dave Tagatac English III Dec. 1, 2000 Canterbury Tales Essay #1 In Geoffrey Chaucers Prologue to The Canterbury Tales, there was a Friar to accompany the party traveling to Canterbury. Hubert, as he was called, embodied the traits from which friars were expected to keep their distance. Chaucer is successful in using this white-necked beggar to bring to the readers mind corruption, wealth, greed, and lechery, all hypocritical and immoral characteristics for a man of the church to possess. Although he is a merry man, full of joy and wantonness, these are mere irrelevancies when assessing Huberts value of character as a friar. Throughout Chaucers description of the Friar in the Prologue, Huberts corruption is evident. Probably the Friars greatest evil is suggested early in his description and mentioned several times more. When Hubert would marry a couple, he would give each Of his young women what he could afford her. The sexual connotation of this statement is enforced by the fact that He kept his tippet stuffed with pins for curls, / And pocket-knives, to give to pretty girls. Other evidence of corruption, although not as reprehensible as the defiance of celibacy, includes Huberts failure to befriend the lepers, beggars, and that crew, to whom friars were intended to be nearest. The narrator explains that their lack of money makes their friendship simply a waste of the Friars time. A friar is supposed to be poor, only taking what they need to survive, and giving the rest to those impoverished souls who need it. Hubert, on the other hand, was quite wealthy. I have never known the imbibing of alcohol to be a necessity of life, and yet this friar knew the taverns very well in every town / And every innkeeper and barmaid too. The narrator even states outright that his income came / To more than he laid out. Yet another extraneous possession for a friar was the extravagant dress Hubert wore, as contrasted with the rags friars were expected to don. All of these things demonstrate how the Friar, even when obtaining more than he expected, gave very little to the poor, and kept much for himself. This feeling is continued even augmented upon examination of Huberts greed. Highly beloved and intimate was he / With Country folk within his boundary. As mentioned above, he associated not with the poor, But only with the rich and victual-sellers. Anyone from whom a profit was possible was inherently the Friars friend. This greed is indisputable in light of a final piece of evidence. That is that Hubert would actually pay other friars not to beg in his district. Again, these are actions to be frowned upon in any man, let alone a religiously affiliated one. Finally, Hubert can be shown to be a leach, hanging around those from whom he can get money, and depending on them to support his opulent lifestyle. Although he had no permission to hear confession, this was one way for him to make money, and he did not hesitate to utilize it. He even targeted those who werent so wealthy in a never-ending quest for monetary gain: though a widow mightnt have a shoe / Â ¦ / He got her farthing from her just the same. When people of his district had a dispute, the lecherous Friar was there. Hubert could be found taking advantage of any opportunity he could find to make money honestly, or dishonestly. The Friar was well liked, and had a wonderful singing voice, but his contributions to society ended here. He, through his actions, has shown evidence of corruption, immoral opulence, greed to increase this wealth, and a terrible habit of leaching off others. He was considered a man of the church, but he was far from the piety the title friar conveys.

Carbon Nanotubes for Nano-particle Field Extraction Thruster

Carbon Nanotubes for Nano-particle Field Extraction Thruster Using carbon nanotubes as propellant for nano-particle field extraction thrusters Stefan Seuleanu Introduction Carbon nanotubes have been a research focus for more than two decades due to their unique physical properties and have been used so far in a variety of appli- cations. A possible application of carbon nanotubes is their use as propellant for an electric propulsion prototype, the nano-particle field extraction thruster (nanoFET). The nanoFET accelerates and ejects conductive particles in order to provide thrust1 . Its main advantage over other electric propulsion systems, such as ion or arcjet thrusters, is its variable specific impulse and thrust, while maintaining a high internal efficiency1 . Theoretically, the nanoFET propulsion system can be used for a large range of orbital and deep space exploration sit- uations, offering the possibility of decoupling the spacecraft design from the propulsion system4 . However, to date, nanoFETs have not been researched ex- tensively and much of the experimental work is still to be expected. This paper will investigate the possibility of using carbon nanotubes as nanoFET propel- lant by considering their relevant physical properties. By understanding how the nano-particle field extraction thruster works,this account also motivates the use of carbon nanotubes as propellant, despite their current high price. Properties and characteristics of CNTs Firstly, it is important to understand the relevant characteristics that make CNTs desirable for the nanoFET propulsion system. A carbon nanotube is a tubular/cylindrical structure that can be visualized as a wrapped sheet of graphene (one atom thick, two dimensional carbon based hexagonal lattice). Their size is typically a couple of nanometers in diameter and can span many micrometers in length. Carbon nanotubes can be single-walled (SWNTs) or multi-walled (MWNTs). These two characteristics will determine their aspect ratio (ratio between length and diameter), which is generally very high. As will be explained later on, the aspect ratio is a determinant factor that influences the nanoFET performance2,3 . The geometric structure of the nanotube determines its electrical properties. Based on the chiral vector (n,m), illustrated below, there are three main types of CNTs: zigzag, armchair and chiral. When n − m is a multiple of three, then the CNT is metallic, and semiconducting otherwise. Due to their geometry, armchair CNTs are always metallic, while the other types can be metallic only with the right choice of (n,m). Because there is no exact way to synthesize carbon nanotubes of only one geometry, as expected, generally one third of the synthesized CNTs are metallic and the rest are semiconducting 2,3 . Figure 1: CNT type depends on the chiral vector2 . Regarding the nanoFETs, the desired CNTs are the metallic type which implies the necessity for prior sorting before use. Moreover, the synthesized CNTs can contain geometrical †defects† that can be manipulated to improve the thruster’s performance3 . Due to the fact that the CNTs’ structure/geometry minimizes the collisions between conducting electrons, the resulting metallic tubes are highly conductive. Another characteristic is determined by the strong carbon bonds that allow high current to flow at low resistivity. This properties will become relevant when explaining the charging stage of the nanoFET 2,3 . The stages of a nanoFET The acceleration of a particle by a nanoFET can be divided into several stages. By assuming that the particles have been already sorted for the desired thrust, the first stage is the transportation of the particles to the charging pad. The transportation of the particles can be achieved either trough a dielectric fluid or through back pressure, hence the difference between wet nanoFETs and dry nanoFETs. For the purpose of this paper only the wet nanoFETs will be con- sidered, as the research done into dry nanoFETs has so far been minimal. The transportation liquid used for the proof-of-concept tests was silicon oil. After the particle is transported to the charging pad, the next stage is the charging process . Here the conductive particle is electrostatically charged to a desired level 5,6,8 . Figure 2: Single nanoFET emission channel cross section5 The next phase is the lift-off and extraction, which represents the application of an electric field, a potential bias between the electrode and the acceleration gates, such that the particle leaves the charging pad and moves upwards towards the liquid’s surface. At the surface, the particle must overcome the surface tension and get extracted from the liquid. After the extraction, the next stage is the acceleration of the particle trough several stacked gates. The gates have alternating insulating and conductive layers, each providing in theory an electric potential of 1000V, leading to a total of 10,000V potential that accelerates a particle to approximately 10km/s. The particle is finally ejected out of the nanoFET and thrust is produced5,6,7 . Particle behavior in nanoFETs In order to understand the behavior of the particle in a gravitational setting compared to a micro-gravitational setting, it is important to identify the forces that act on the particle at different stages in the nanoFET. The four main forces acting on a particle in a gravitational setting are the electrostatic force, the buoyant force, gravitational force and the drag force. As the cylindrical particle is transported to the charging pad, the liquid provides a horizontal inertial force. This horizontal inertial force is assumed to be low and therefore ignored in the calculations. After the nanoparticles are transported to the charging pad (electrode), they are electrostatically charged; thus contact with the electrode is necessary. If the contact is horizontal, along the length, then the charge of the particle is described by6 .: q0,cy−h = 2Ï€rlÃŽ µl El However if the contact is at either ends, so the particle is vertical on the electrode, the charge is the following6 .: l2 q0,cy−v = Ï€ ln( 2l ÃŽ µl El When the cylindrical particle is vertical on the charging pad, it gains more charge and it also requires less electric field to move upwards, as seen in the figure below6 . Figure 3: Vertically vs horizontal oriented particles a) ratio of acquired particle charge; b) ratio of required lift-off electric field6 In order to orient a particle from horizontal to vertical on the charging pad, an intense electric field focused only at one of the particle’s ends is applied. The fabrication defects that are usually present at the ends of CNTs may help to change the orientation of the particle on the electrode, requiring less electric field to create a moment that rotates the CNTs vertically. Additionally to the gravitational force, while still on the charging pad, the particle has to overcome the adhesion and electric image force in order to achieve vertical lift-off5,6 . After the particle leaves the charging pad, it has to move vertically trough the viscous liquid to the liquid surface. Therefore, the adhesion force and the electric image are no longer present; however the drag force now slows the particle’s movement. For a cylindrical particle the formula for the fluid drag used in the nanoFET calculations is given by6 : 2π µl lv D = ln( l ) + 0.193 While moving through the liquid, the particle loses charge as described by q(t) = q0 exp(− t ), where Ï„ = ÃŽ µl 5,6 . Because the particle moves fast through Ï„ ÏÆ'l the liquid, the charged loss is overall assumed to be negligible. Generally, the particle’s equation of motion is described by6 : dv (mp + K ml ) dt = q(t)El − D + Fbuoyant − W. The above equation also takes in account the added mass that is accelerated with the particle where K is a coefficient that depends on the geometry of the particle, while mp is the mass of the particle and ml is the mass of the liquid. In a laboratory gravitational environment the gravitational forces are minimal compared to the dominant drag and electrostatic forces. In a micro-gravitational environment the gravitational force and the buoyant force can be neglected5,6 . Performance and particle size For characterizing the performance of the nanoFET electric propulsion system, the space industry uses specific impulse and thrust-to-power ratio as indica- tors of performance. The specific impulse is the impulse delivered per unit of propellant consumed. In order to achieve a certain thrust, the systems that have higher specific impulse consume less propellant than the ones with lower specific impulse. For the nanoFET system the specific impulse increases as the charge-to-mass ratio of the particle increases. Thurst-to-power ratio describes the amount of thrust outputted for a specific power provided4,6 . 1 q 1 T 2 mp 1 Isp = 0 (2Vo p ) 2 ; = ( ) 2 P Vo q Moreover, the internal efficiency is given by4,6 : 1 T ÃŽ ·int = 2 g0 P Isp There are several factors that can influence the performance or the mode of operation of the nanoFET. First of all, the horizontal inertial force that the particle gains from the transportation liquid is assumed to be negligible. How- ever, this is not necessarily the case and further research needs to be conducted in order to determine its influence. Another important factor is the presence of Taylor cones and surface instability when a high electric field is present near the liquid’s surface. These cones can eject droplets and reduce the performance of the nanoFET. In order to mitigate the surface instability and the ejection of droplets, an experiment has been done to analyze how different particle shapes influence the minimum electric field needed for the extraction process. The ex- periment consists of various vacuum electric fields applied to spherical 800 µm and cylindrical 300 µm diameter and 1.5mm length aluminium particles with a total silicon oil fluid gap of 12 .7mm. As seen in the figure below, cylindrical particles can be extracted before the Taylor cones form5,6,7, . Figure 4: Taylor cone formation and particle extraction6 Furthermore, further study into the charge-to-mass ratio revealed that, for cylindrical particles, charge-to-mass ratio increases as aspect ratio increases. Therefore, at large aspect ratios, the needed extraction electric field decreases as seen in the following figure. For this reason increasing the aspect ratio of the particles increases in turn the Isp and the overall internal efficiency6 . A good candidate for further research are the CNTs due to their cylindrical Figure 5: Cylindrical particles’ vacuum extraction field simulations6 shape, high aspect ratio, good charge-to-mass ratio and fast charging. By choos- ing different CNT sizes to be used with variable gate potentials, the nanoFETs’ Isp range is theoretically very large compared to other electric propulsion sys- tem such as ion thrusters or hall thrusters. Similarly, the thrust-to-power varies greatly, which offers the flexibility of using the same propulsion system for mul- tiple missions or to perform unplanned trajectory changes at a low propellant expense. These are theoretically achieved while maintaining a high internal efficiency that is usually above 85%. For the following CNTs: nanoFET par- ticle1 16nm diameter, 3 µm length; nanoFET particle2 4nm diameter, 3 µm length; nanoFET particle3 1nm diameter, 3 µm length, the expected Isp and Thrust-to-Power ratio is illustrated4,5 . Figure 6: Thrust-to-power ratio for large specific impulse range4 Figure 7: Internal efficiency for large specific impulse range4 Discussion Apart from the large specific impulse range at high internal efficiency that pro- vides great flexibility to design a multitude of mission phases based on just one propulsion system and to accommodate for unforeseen scenarios, the nanoFETs have other important advantages over other electric propulsion system, such as potential longer operational lifetime, their geometric scalability and the fact that the system is highly integrated. The longer operational lifetime is due to the fact that the CNT particles or any other conductive particles are charged electro- statically and not ionized which eliminates the need for cathodes and eliminates charge exchange collisions that are the main lifetime reduction factors5,6 . However, there are still a multitude of challenges ahead until a fully functional prototype will be achieved. First of all, the experiments done so far that demon- strated particle transportation, charging and lift-off were conducted using mi- crometer size particles such a s Aluminum, Titanium and Indium. Although theoretically the CNTs can greatly increase the performance, no nano-size par- ticles have been experimentally used so far. Experimenting at the nanoscale might sometime reveal new problems that were not present at the micron level. Also, it is generally desirable that a quantitative experimental analysis is done in order to understand how a multitude of particles with different character- istics perform. In this way it could be determined what particle shows the most promise, although CNTs have a strong theoretical advantage mainly due to their charge-to-mass ratio. Another important factor to investigate is how the charging process changes as the size of the particle decreases to the several nanometers; the main concerns being conductivity and the contact area with the electrode. Furthermore, an investigation should also be conducted regard- ing the transportation liquid. So far, it is uncertain if a fully dielectric liquid is always desired over a slightly conductive liquid. Moreover, different liquids should be tested in order to experimentally understand how the viscosity of the liquid influences the space charge current5,6,7,8 . Finally, from an academic point of view it would be desirable that both the theoretical and experimental papers are published in a peer-reviewed journal. Conclusion Overall, the nanoFET propulsion system shows great promise due to its high specific impulse range and inherent scalability. Although it is a new concept, the most important processes such as particle transportation and charging have been already demonstrated. However, there are still a multitude of experiments that need to be conducted in order to fully understand the behavior of the system under a wide range of factors. Another interesting prospect for the nanoFET technology is their possible use , not only in the space industry, but also in medicine. The nanoFET technology can also be used to accelerate particles and inject them through cellular walls to deliver drugs. For these reasons, the nanoFET technology is an exciting and potentially rewarding research subject. References 1. Gohardani O, Elola CM, Elizetxea C. Potential and prospective imple- mentation of carbon nanotubes on next generation aircraft and space vehicles: A review of current and expected applications in aerospace sciences. July 2014. Elsevier. Progress in Aerospace Sciences 70 (2014): 42-68, ISSN 0376-0421, http://dx.doi.org/10.1016/j.paerosci.2014.05.002. 2. Loiseau A, Launois P, Petit P, Roche S, Salvetat JP. Understanding Car- bon Nanotubes. 2006. Springer. ISBN-I3-978-3-540-26922-9. 3. Dresselhaus MS, Dresselhaus G, Avouris P. Carbon Nanotubes: Synthesis, Structure, Properties, and Applications. 2001. Springer. ISBN 3-540-41086-4. 4. Liu TM, Musinski LD, et al. Nanoparticle Electric Propulsion for Space Exploration. 2007. American Institute of Aeronautics and Astronautics. Re- trieved from: http://pepl.engin.umich.edu/pdf/STAIF2 007.pdf on1stof J une2015. 5. Liu TM, Musinski LD, et al. Nanoparticle Electric Propulsion: Experi- mental Results. 2007. American Institute of Aeronautics and Astronautics. Retrieved from: http://deepblue.lib.umich.edu/bitstream/handle/2027.42/76874/AIAA-2006-4803- 539.pdf ?sequence=1 on 1st of June 2015. 6. Liu TM, Musinski LD, et al. Theoretical Aspects of Nanoparticle Electric Propulsion. 2006. American Institute of Aeronautics and Astronautics.Retrieved from: http://pepl.engin.umich.edu/pdf/AIAA-2006-4335.pdf on on 1st of June 2015. 7. Liu TM, Musinski LD, et al. Developmental Progress of the Nanopar- ticle Field Extraction Thruster. 2008.American Institute of Aeronautics and Astronautics. Retrieved from: http://www.umich.edu/ peplweb/pdf/AIAA- 2008-5096.pdf on 1st of June 2015. 8. Liu TM, Musinski L, Gilchrist B, Gallimore A. Electrostatic charging of micro- and nano-particles for use with highly energetic applications. 2008. Elsevier. Journal of Electrostatics. doi:10.1016/j.elstat.2008.11.001

Tuesday, August 20, 2019

How Important is Being Earnest? Essay -- Literary Analysis

Oscar Wilde is the author of the comedic play, The Importance of Being Earnest, which is a drama about two people who hold double lives trying to be the same person. While Wilde intended for his play to have people filling the theatre with laughter he conveys a deeper meaning. By looking closely at the characters in the play readers can see everyone is very selfish or egocentric. All the events that occur between the characters happen because they are only thinking about themselves. The lives of all the characters mingle together all due to this one character named Ernest who is first created by the character, Jack, for personal benefit. Ernest is spelled different from the word â€Å"earnest† which means serious in purpose or sincerity of feelings. Wilde uses this play on words to create a satire on the morals of people during his time period. The characters in the novel do not display earnestness but disrespect. The main characters will find out that being sincere and honest is better for them than lacking respect for others. The first character readers meet is Algernon, a friend to Jack, who is preparing for his aunt, Lady Bracknell, to arrive. After a conversation with his manservant he says â€Å"Really, if the lower orders don’t set us a good example, what on earth is the use of them? They seem, as a class, to have absolutely no sense of moral responsibility† (Wilde 6). Algernon believes people of less fortune have fewer morals. For example marriage is less important. Algernon displays hypocritical characteristics because he is going to try to base a marriage off of a fake identity. Another subtle hint to Algernon’s selfishness is when he eats all the cucumber sandwiches meant for his aunt. As he is sitting there talking to Jack he... ...to build relationships. They are building the relationships based on lies and deceit rather than being earnest which would build a stronger relationship. At the end of the play all is well and the truth comes out. The characters have finally learned their lesson the being earnest is important. It is not the name that is important but their qualities as a person. The characters can now live happy, fulfilling, honest lives with their spouses. Wilde portrays how morals are important through a comedic satire. Works Cited Wilde, Oscar. The Importance of Being Earnest. New York: W.W. Norton &, 2006. Print. JACOBS, KATHERINE. "Shakespeare's MUCH ADO ABOUT NOTHING 5.4.109-18." The Explicator 59.3 (2001): 115. Literature Resource Center. Web. 4 Apr. 2012. Doniger, Wendy. â€Å"Self Impersonation in World Literature† Literature Resource Center. Web. 4 Apr. 2012

Monday, August 19, 2019

The Failings of Mr. And Mrs. Elliot Essay -- Mr. and Mrs. Elliot Essay

The Failings of Mr. And Mrs. Elliot      Ã‚   This cynical look at a less than ideal marriage keeps the reader at a distance. The opening sentence startles in its baldness "Mr. and Mrs. Elliot tried very hard to have a baby" and the second sentence destroys any illusions that the Elliots are enjoying this by stating that "They tried as often as Mrs. Elliot could stand it"(Hemingway 85).    The second paragraph uses one long, oddly convoluted sentence to describe their courtship and subsequent marriage. It isn't until the third paragraph that either is referred to by a first name and then young Mr. Hubert Elliot's career is discussed. Mrs. Elliot's age has already been revealed, she is forty, and now Hubert's age is given as twenty five. This disparity in ages is explained by the fact that Hubert has been keeping "himself pure so that he could bring to his wife the same purity of mind and body that he expected of her"(85). The very thing that girls his age laugh at is what endears him to his friend at the tea shop, Cornelia.    She, too, is quite pure and they are delighted to have found each other, even if his mother cries over their marriage. Later she "brightened very much when she learned they were going to live abroad"(86). Perhaps she's relieved that the newlyweds will be out of reach of the wagging tongues of neighbors and friends.    The happy couple spends much time kissing and congratulating themselves on having remained pure. Apparently marriage wasn't in Hubert's plans, he can't even "remember just when it was decided that they were to be married"(86). But they do marry and the wedding night proves to be disappointing, the impression being that two such pure souls have no clue how to make love. A... ...friends of her own, concentrating instead on making that baby and typing Hubert's poetry. There is also a tendency to accept at face value some things that would arouse suspicion in a more thoughtful (or less desparate) person. "Hubert explained to her that he had leaned that way of kissing from hearing a fellow tell a story once"(86).    It might be easy to feel sympathy for such deluded people, creating their own traps and convincing themselves that they are so very happy. But the slightly sarcastic edge of the narrative combined with the distance maintained throughout instead works to encourage contempt. At the end of the story it's easy to dismiss the Elliots as having made their bed. Now they'll just have to sleep in it.    Works Cited Hemingway, Ernest. "Mr. and Mrs. Eliot." The Short Stories. New York: Scribner Paperback Fiction, 1995.   

Sunday, August 18, 2019

Reality Versus Perception in the Kasdan Films, Grand Canyon and Mumford

Reality Versus Perception in the Kasdan Films, Grand Canyon and Mumford All of knowledge is founded on axioms: assumptions that are agreed upon for stability. However, since those axioms are assumptions and cannot be proven without a doubt, nothing ca truly be known with absolute certainly. Still, in order to carry on with life, assumptions have to be made. Knowing this, the task becomes making assumption that are more educated and, given the lack of certainty, ones that matter. Furthermore, the assumption of others can be examined more accurately with this knowledge in mind. The most important of these assumptions, and in many cases points of debate, is the nature of reality. The old world thought the matters of the spirit to be truly real, or ethereal, as opposed to the physical world. The modern period, on the other hand, held that sense perception was the only evidence that was concrete and that reality was only that which could be corroborated by sense perception. This gradual shift that occurred endeavored to transform humanity’s vi ew of reality from the ethereal to the physical. The fact of the matter, however, is that the modern period had no more indubitable evidence for believing in a physical reality than the people before it had for believing in an ethereal reality. As a result, the current time of postmodernism is fragmented in a disarray of those two realities and countless variations thereof. The world today is trying to figure out constantly what actual reality is, whether it truly is ethereal or physical. This trend can be observed in media to a large degree. The case here is that the Kasdan films Grand Canyon and Mumford are portraying this social struggle in the bifurcation of postmodernism.... ...lso that the reality of events throughout time is variable and relative. The nature of things commonly understood as good or bad are not necessary one or the other, but may change. Reality is a matter of perception. Whether reality is truly ethereal or actually physical in nature is determined, for the duration of life, by the living. Given this, it can also be conceived that no one knows the nature of what is happening to anyone as being positive or negative. No one even knows whether the nature of events is a constant factor, since finding that reality may be variable insinuates also that the nature of anything and everything may also be subject to change. So in truth, this inquisition, in some ways, is back at the starting point. However, there is an advantage in knowing what potential ignorance exists as opposed to being ignorant of that very ignorance.

Saturday, August 17, 2019

Cause and Effect Essay

Internet technology has created a hindrance in people’s lives. First the use of technology creates nothing but a distraction. In the article â€Å"Is Technology Making Us intimate Strangers? †, Jonathan Coleman says , â€Å" If someone hasn’t left us a phone message or fax, there is always the chance that an e-mail awaits. I can’t even finish this essay without checking- three times already- to see if another one came through. † This is completely true, in the tome it took me to quote that, I stopped and checked my phone twice. Another example of technology being a distraction is by talking on the phone or checking a text message which can be a distraction as well as deadly. Secondly how the use of technology enables people to have privacy. It’s crazy how jobs, schools or anyone that wants to know anything about a person can easily find out through the use of internet technology. Example of that is through a social network. If someone wants to know where a person lives, where they go to school, or what they are doing, they could find out with the touch of a finger, stripping people from any sort of privacy. Finally social interaction, Jonathan Coleman states â€Å"Technology, for the most part, creates the illusion of intimacy. As marvelous as it can be, it also foils us. It keeps us from the best of ourselves and enables us to avoid others. It makes us into intimate strangers. † A prime example of that is the use of internet dating, technology takes away the term dating, getting out knowing somebody, to have a face to face conversation. Instead we stay indoors with our computers or any sort of technology talking to our computer loves.

Friday, August 16, 2019

Causes of Happiness

Happiness is an emotional or affective state that can be individual or shared with other people. Each person has own definition of happiness. For example, some people think that happiness comes from having a lot of money, and some think that happiness can come from simple things such having a friend.Happiness can affect your health, the people around you, and it can make you have a positive life. There are three causes of happiness such as being successful, eating chocolate, and being optimistic. The first cause of happiness is being successful.Successful life can lead to happiness. For instance, if you are a successful student, you are going to be happy. That is because you are going to feel accomplished which is one of the reasons that lead to happiness. Being successful could also mean having good relationships with other. In other words, if you show good manners everywhere you go, you will make people like to have a friendship with you. As a result, you are going to have a relati onship with your friends, and friends can be one of the reasons that lead to happiness. The second cause of happiness is eating chocolate.Eating chocolate can make you be happy. For instance, researcher have found that chocolate has the property of increasing levels of some hormones. These hormones can cause feelings of happiness and well being.Also, the researchers found that eating 40 grams of dark chocolate every day for two weeks can reduce the stress. In other words, the levels of stress hormones will be reduced which can make you feel happy. The third cause of happiness is being optimistic. Optimism is one of the reasons that lead to happiness. Optimism is a hopefulness and confidence that things will work out.Also, it can help us to move from the past and not fear the future. If you are a pessimist, you are going to think that things will not work out. As a result, the pessimist can lead to less happiness and make you have sadness in your life.In conclusion, it seems that we have three causes of happiness such being optimistic, eating chocolate and being successful. Happiness is very important to our life because it can make our life meaningful. It can affect our life and the people around us, so people have to be happy and optimistic in order to have a comfortable life.

Thursday, August 15, 2019

How Do Certain Food and Beverage

Despite all the conventional methods of analyzing the customers with all the physical and social and other factors, the actual statistics seem to differ tremendously from the estimated outcomes. This is because we as humans seem to bank heavily on emotions. Once the customer has some sort of emotional attachment with the outlet for whatsoever reasons, he is not going to opt for other places. The customer might now be considered loyal to the outlet. The customer wouldn’t prefer going to any of the competitors because he feels he has some sort of bond with the outlet. This emotional umbilical cord is very powerful as it is one of the easiest and the most effective ways to maintain customer loyalties. As they say, it is easier to retain the existing customers than it is to create new ones. The existing customers would always walk in with that feeling of homeliness and once this feeling of theirs is respected and catered, all the outlet has do is cash in. Existing customers don’t mind paying a little extra also because they’ve already grown used to the ambience and the way the outlet is run. Therefore, it should be profoundly important for the hotels and restaurants, to see to it that they lock in the customers as their regular guests. The hotels have to work hard to make sure that the customers don’t take away the business elsewhere. The loss of a regular customer is colossal. The hotel is just not losing that one customer but a lot more than that. All those people whom he had recommended the hotel in course of years would also develop negative thoughts and opinions about the outlet. This might be a very serious issue and often devastating for the hotel chains. Loyalty as such is the key factor in most businesses, but its impact is more clearly visible in the business of hospitality and hotel management. When compared to several other businesses, the one fact that stands out here is that the hospitality industry has a lot to do with how the customer actually feels about being at the place. This might include the food, the ambience, the customer satisfaction and several other factors. Hospitality has more to do with experience as against those of other industries who just sell products. There can be many ways in which this can be done, some hotels prefer giving free gifts, some give special privileges to their regular customers, some others give huge discounts. All these methods are simply aimed at encouraging customer loyalty. The hotels and restaurants should never miss a chance on maintaining and pleasing loyal customers given the fact that this emotional attachment is so very delicate yet powerful enough change the very course of several businesses. Research Problem: It is because of these above stated reasons that it becomes immensely important for the managers to study the science of loyalty management and learn how to implement it thoroughly. Discussion: Important concepts and theories, the background of the study: In simple terms, it can be said that in spite of all what the company the customer has an inherent tendency to keep looking for better alternatives, the analogy here is given by Leahy where the characteristic customer behavior is compared to that of a cat. A dog considered being man’s best friend because come what may it does not swerve its loyalties. However the customer behaves more like the cat and is always on the lookout for softer and more comfortable lap. The need of the hour is that the hotels should see to it that they provide this soft lap to the customers and always keep increasing the standard of their services. Leahy here compares the restaurants to the airlines; the airlines have been far more successful in maintaining loyal customers than the hospitality industry. Airlines have several clubs where the members are classified as gold, silver or other such members. The members of such clubs are offered free up gradation from economy to business class if the seats are free. However no such practice is noticed among the hotel managements. The article takes evidence from US consultancy Colloquy, noting that restaurants are lagging far behind other businesses in developing loyalty schemes. The article notes that in the United States, only 27. 2 million customers are part of restaurant loyalty schemes, while airlines have over 254. 4 million members for their loyalty schemes. Leahy further emphasizes that loyalty issues are to be taken very seriously in the restaurant business and it is very important to retain regular customers. The General Approach: There are many ways to retain regular customers, one such prominent way is the loyalty card, a technique which has now caught on even in big showrooms and jewel stores. The simple technique here is that every time the customer buys something, he is given certain points and once these points reach a certain value, the points can be exchanged for discounts or special offers. This not only keeps the customer coming back to your store but also helps in maintaining good relations. Once again this idea was an innovation of the aviation industry and it still needs to be implemented to a greater extent in the hospitality industry. According to CEFF (2007), loyalty cards schemes are a key factor in determining choice of hotel, airlines and restaurant chains by leisure travelers. Surveys have revealed that even though there are some customers who don’t quite bother about these loyalty cards, a good percentage about seventy percent of them admit that the loyalty cards played prominent roles in them determining their hotel or airlines. Literary Reviews and Opinions: Gomez, Arranz and Cillan (2006) argue that these loyalty programs yield two important results of interest, which may be applied to the hotel and restaurant hospitality sectors. Such a program creates to genres of customers. The first class of customers includes those who display more behavior loyalty than the others simply because they are emotionally aware that the hotel considers them more important than their counterparts which are not enrolled in any of the loyalty schemes. As in all businesses, emotion plays a very prominent role even in the hotel and management industry. Yet another thing that needs to be borne in mind is that the customer will not simply walk in to your outlet just because you have all these cards and offers. For example, however captivating and encouraging might be the scheme; the customer will come to your restaurant only when he feels like eating. You can never force the customer to increase the number of his visits, directly or indirectly. Research that compares consumer behavior before and after the introduction of a loyalty program show that there is no real difference in the number of visitors, or the amount of purchasing done (Gomez, Arranz, & Cillan, 2006). Here it is once again argued that loyalty program don’t quite generate new loyal customers but just help in retaining the existing loyal customers. As in any other business, the sole objective and the motive behind your business should be very clear, for example, if the customer doesn’t like your product, then all the management tactics in the world will not help him come to you. The bottom line is that what you offer the customer must stand up to his expectations. Trust and satisfaction are won by genuine effort and determination, there are no shortcuts, and the customer is smart enough to figure out what the actual standard of your restaurant is. According to Gomez, Arranz and Cillan (2006), effective loyalty can only come from customer attitudes such as satisfaction, trust and commitment. Loyalty based on simple repeated behavior is not very effective. Ethical Considerations: Unwanted effects of biased management: Some researchers argue that even though loyalty is a very important issue, it is very difficult to impress the customer through these roundabout techniques; the management needs to focus more on other basic issues like the maintenance and the quality of service. All these schemes and offers can only assist the growth, they can never be the sole reason for the growth and a sensible manager should never depend upon any of these. Lacey and Sneath (2006) argue that customer loyalty programs are not always fair to all consumers. The argument is assisted by the fact that such loyalty schemes only focus on a certain class of customers and not all customers. This creates negative hype and ill feeling among. The firm spends all the resources on pleasing the existing customers whom they assume to be loyal where as the new customers who might prove to be loyal customers in the future are just left to themselves. If this methodology is practiced in the long run, the organization might stand to lose many customers, the organization was so very considered about pleasing the existing customers that they forgot that they even have to generate new customers. â€Å"One of the basic principles of the company is remembering what it is that guests prefer when they are in your hotel,† explained (Ritz Carlton) spokeswoman Vivian Deuschl. Such an approach can even be dreadful at times. It is argued that the same quality service should be given to all the customers. Never should the restaurant make the mistake of pleasing one class of customers at the expense of others. Such a treatment might be very pleasing to the regular customer but even he will hesitate to recommend the restaurant to others because he knows that new customers are not treated well over there. Apart from all the above-mentioned ill effects, this practice is strongly condemned even on ethical grounds. The safest and the best alternative are to provide uniform treatment throughout to all the customers. This generates a positive attitude and helps a lot in business. There is no substitute to genuine hard work, determination and honest implementation of policies. As Jack Welch in his book Winning quotes â€Å"sorry, there are no shortcuts†. Hypothesis and Questions: The prime objectives: Rather than concentrating on these hypothetical concerns, the restaurant should be bothered more about improving service delivery, bakery products, and cooking. Lacey and Sneath further argue that customers who are not a part of such loyalty schemes are often discriminated against and this is very unpleasant for the customer as well as a loss in revenue for the management. Langenderfer & Cook (2004), Petty (2000) throw light on a very important aspect here. The customer databases are rich with information and are excellent resources and if by chance this data ends up in wrong hands, t can be very taxing for the customers. If such a thing happens, then it would be a clear exploitation of customer rights and a breach of moral and ethical values. The customer would then obviously hesitate to become a member of any such loyalty schemes in future. Wendlandt & Schrader (2007) come up with yet another intriguing question, they argue that all these schemes at times might even backfire and in fact cause more loss to the organization. As an able manager, the first that needs to be firmly affixed in mind is that we as humans are more effected by emotional happenings than anything else. Once the person is emotionally troubled or if he even perceives that he is being manipulated, even the most loyal of the customers will give up. The customer might get frustrated by all these and begin to think that all these tricks only serve as gimmicks and in fact react exactly in a way opposite to what is expected of him. Smartly designed loyalty schemes however can actually avoid reactance of this type. For example, a loyalty scheme that offers long-term financial rewards that have to be gathered over repeat visits will probably avoid reactance (Wendlandt & Schrader, 2007). However, long-term loyalty schemes can also be less effective at retaining regular customers. Kirby (2007) has yet another way of seeing the same scenario, the argument here is that it is more beneficial to serve customers as people rather than targeting on their customer profiles. The argument here is that rather than treating loyalty as just another part of the charm game, the hotels should earn repeat business by offering excellent services based on remembered and recorded client preferences (Kirby, 2007). If hotels invest in tracking guest preferences and provide a superior service through the use of Customer Relationship Management (CRM), the customer will automatically be retained. Weinstein (2004) further argues that the ambience and the feel of the place are also very important. Always remember that the customer might forget what he came for, why he came, when he came etc but he is never going to forget how it felt to be there with you. In the book the â€Å"Ice Cream Maker†, a book on the concept of six sigma, the author argues that in a departmental store or a shopping mall, it takes an average of seven to eight seconds for the customer to pass by your restaurant, it is in this minute fragment of time that we have to impress the customer that our outlet is actually worth a visit. To make the customer ‘feel’ something is an enormous challenge in its own right. Therefore, it is well worth going the extra mile to provide extra amenities to impress guests into engaging in repeat business (Weinstein, 2004). Some of the 5 star chains in Dubai follow this strategy, hoping to get repeat business by pampering even walk-in customers. Research Questions: To summarize we can say that all the literature on loyalty is divided into two categories both conflicting each other. The first category, is those who advocate the loyalty schemes to lock in customers and make sure that they patronize and prefer certain restaurants in place of the other. Some researchers even argue that such a type of management might even be unethical. The second category of advisors are those who emphasize on the importance of personalized service, remembering customer preferences, and offering amenities to keep customers coming back. They note that rather than discriminating customers, their stand is that hotels, restaurants and other businesses should keep service standards high across the board. As a manager we are faced with the question that when and to what extent which of these methodologies or logics are to implemented? What is to be given more importance and how are customers, both old and new to be dealt with? Should the approach to both these parties be same or different? What is it that needs to be done so that all the parties are happy and content? How are we going to satisfy the emotional requirements of our customers? Jang and Mattila (2005) throw light on yet another trend. Their basic argument is that the manager must learn to understand the customer needs and requirements and react accordingly, for example, if the customer is expecting monetary benefits, then he must simply be given so, instead if the hotel argues that the customer be given only the free spa session or a free buffet lunch against his will, then it is only obvious that none of the parties is happy. The customer is displeased because he is given something free of cost something he actually has no desire for. The hotel has used up its employees and other resources for the same purpose, which was not at all fruitful. Thus, such a decision has a negative impact on all parties. Jang and Matilla further note that at times immediate cash discounts are also not the solutions to the problem. Also, while customers may want immediate rewards, it usually suits managers to delay gratification in order to ensure repeat business. Also, there is less guilt associated with luxury rewards if they’ve worked up to them over a period of time. It is also noted that there is a very strong potential for developing such programs in the hospitality industry. The transactions involved and the formalities taken up during the process of loyalty offers should be made very convenient and comfortable. The customers should not be penalized to show their loyalty cards every time; the hotels should remember the customers and work towards serving them better. Data Management and Analysis and Budget considerations and timelines: Statistics will provide all sorts of data from all sorts of places. This data might vary over decades of research or even more, the right management comes from the fact that the manager should be able to pick up the right data and study it accordingly, wrongly directed research or haywire policy implementation is sure to spell doom for the company. Therefore, it is of profound importance that the right data be chosen from all perspectives, the implementation schemes should not be so costly that the management suffers because of these, after all management is all about producing the best possible results in the minimum possible expenditure. Also, the time limits should also be adhered to very strictly. What might be a huge success in summer might be a complete failure in winter. If the set goals are not achieved within the given time limits, then the entire purpose of research is flawed. Conclusion: There is no dearth of literature as far as the loyalty issue is concerned. Managers realize very well that there is more to management than just analyzing theories, real problems need real and innovative approaches, and not everything can be solved from the books. Able managers know for a certainty that all what is in research papers is just conjectures and even if a particular scheme or technique worked very well in a particular hotel or restaurant, there is no guarantee that it will produce the same or similar results elsewhere or even the same hotel the next year. Trends change, people change, their needs and expectations change, every year researchers come up with new theories. The key to being a successful manager is to have the right instincts and realize where to draw the line. It might be noted that the manager should not go to extremes, as an example he might be so puffed up with confidence that he turns a deaf year to the researchers or for that matter is so engrossed in the research that he forgets that he has to deal with real life situations. Coming to the issue of hotel management and the hospitality industry, the first and the foremost thing that should be firmly affirmed in the mind is that unless and until the product and services are up to the mark and stand valid in front of the customers’ expectations, no amount of management hoopla can help the cause. The hotel management should be more concerned about the quality of service and other basic but very important factors. Only when these issues are properly and sensibly addressed to and resolved can the management think of anything else. The loyalty considerations are also to be dealt with great care and delicacy. It is but natural that the older customer will expect better services and the new customers would want their privileges to be on par with those of everyone else. This is where the elegance of the manager comes handy. The manager should be able to glide between such scenarios always keeping in mind the benefit of the employees and should also be successful enough to generate the maximum possible revenue.

Kinesiology

The movement that the paper shall discuss is the ‘hammer throw’ â€Å"The modern or Olympic hammer throw is an athletic throwing event where the object to be thrown is a heavy steel ball attached with wire (maximum 4 ft (1.22 m) to a handle.† (Farlex Inc., 2007, p.1) The objective of the feat is throwing the steel ball at the farthest distance. â€Å"The two most important factors for a far throw are the angle of release and the speed of the ball.† (Farlex Inc., 2007, p.1)For an athlete, it is important for them to be aware of every muscle movement that happens during the process of hammer throw. These phases are important for a smooth transition of muscles from one stage to another to execute a correct and efficient movement. The next part will highlight the five phases involved in hammer throw. In particular, the following phases will determine the relevant muscles involved in the process.The first phase involves the stance phase. There is minimal amount of movement in this phase that is why muscles remain at status quo. â€Å"Due to the minimal amount of movement in this phase, the majority muscle position maintenance throughout the body should be accomplished through isometric contraction.† (www.mhhe.com/floyd16e, p.196)The next phase involves the preparatory phase. In hammer throw, â€Å"concentric contractions occur in their anatagonist muscles in this phase.† (www.mhhe.com/floyd16e, p.196) The joints involved are the shoulder and elbow in which their actions represent a horizontal hyperextension and extension respectively. In addition, the agonists muscles involve in the process are posterior deltoids and latissiumus dorsi and triceps brachii (shoulder and elbow)The third phase talks about the movement phase. â€Å"It is the phase in which the summation of force is generated directly to the ball, sport, object, or opponent, and is usually characterized by near-maximal concentric activity in the involved muscles.à ¢â‚¬  (www.mhhe.com/floyd16e, p.197) With hammer throw, this is the process wherein the person starts rotating the body which is called ‘turns’.â€Å"You must try to utilize inertial forces of the hammer in the single by riding the ball and being passive with the ascending hammer, while avoiding activity with the pelvis and legs.† (Larry, 2000, p. 1) In addition, â€Å"After running through the high point of the hammer, you must complete the turn on the ball of the left foot by actively driving back to double support as soon as possible.† (Larry, 2000, p.1)The next phase involves the follow-through phase. â€Å"In this phase, often referred to as the deceleration phase, the velocity of the body segment progressively decreases, usually over a wide range of motion.† In the process of hammer throw, the joints involved are the shoulder and elbow. The actions involved are a horizontal flexion and flexion for the shoulder and elbow respectively. The agon ist muscles involved in the process are (1) anterior deltoids and Pectoralis major for the shoulder and (2) biceps brachii for the elbow.The last phase is the recovery phase. â€Å"The recovery phase is used after follow through to regain balance and positioning to be ready for the next sport demand.† (www.mhhe†¦, p.197) For hammer throw, the individual after the follow through stage slowly goes back to status quo as both muscles in the elbow, shoulder, hips, and legs relax to prepare for the next throw.In the process of hammer throw, an individual might sustain an injury due to lack of stretching or failure to follow the proper process in hammer throw. Injuries related to hammer throwing include (1) strains, (2) cramps, (3) calf muscle injuries, (4) sprains and (5) elbow and shoulder muscle related injuries. Thus, it is very important for a hammer thrower to constantly warm up for the sport and at the same time follows effectively every step mentioned by the coach for i njuries to be prevented.ReferencesBrainmac. Movement Analysis in Sports Coach. Retrieved October 21, 2007 fromhttp://www.brianmac.co.uk/moveanal.htmFarlex Inc. (2007) Hammer Throw in The Free Dictionary. Retrieved October 21, 2007 fromhttp://encyclopedia.thefreedictionary.com/Hammer+throwingJudge, L. (2000) A Technique Analysis of the Hammer Throw for Men & Women. RetrievedKinesiology. Retrieved October 21, 2007 from http://www.mhhe.com/floyd16e Kinesiology Al Reyes married and has a step child and I child of his own has done a lot in his lifetime. His jobs vary from working in a cubicle in his early year to coaching high school sports teams to now teaching and coaching the water polo team at Santa Ana College. His life stories have had a vastly large impact on me, he made me realize that life is not always about money, although with it life would be a lot easier, but all you really need is people and things you love and your set.What I really enjoyed bout having him in the class was that he made you listen but not in the way an average teacher would he made you intrigued in whatever it was he was talking about. Although I don't want to become a teacher later in life he made me rethink this. Response to Brian: I agree with Brian I have put a lot of thought into becoming a teacher/coach but never knew what to teach/coach and who for.Mr. Reyes has shed some light and has really been making me think hard, asking myself if teaching is actua lly what I want to do with my life. Have little money but be content with what I'm doing, impacting kids lives in such a way that they don't even know, it sounds just about equally awarding to me.My high School basketball coach/Spanish teacher has changed my life in so many ways, from being captain of her basketball teaching me the importance of teamwork, dedication and hard work can take you a long way to my teacher making me work hard. She was also very close to me I considered her more as a friend in ways she was always looking out for me, driving me to go to college, finding me a place to live. If I change someones life the way she has changed mine I know life will be amazing.

Wednesday, August 14, 2019

Brain Tumour Glioblastoma Multiforme Problem Health And Social Care Essay

GBM normally affects people who older than 50 old ages old although the disease can happen in patients from all age group [ 2,25,28 ] . Patients suffer ictus, concern, ocular perturbation and sometimes personality alterations which can do great emotional hurt [ 25,30,31 ] . The average endurance of GBM patients is hapless, with about 12 to 14 months [ 7 ] . At this minute, the exact causes of GBM still remain vague to the scientists. Figure 1 GBM tumor is normally found in frontal and temporal lobe. Beginning: hypertext transfer protocol: //ebsco.smartimagebase.com/brain-tumor/view-item? ItemID=4027 Accumulative Word Count: 131 Possible Treatments Surgery Surgery is normally the initial measure to handle GBM by taking every bit much tumor as possible. It is non healing but aims to cut down the tumor ‘s size every bit much as possible so that other therapies right after the surgery can be more effectual. Furthermore, surgical resection Acts of the Apostless to alleviate hydrops by debulking tumor every bit good as being a alleviative intervention for neurologic symptoms such as ictus activity [ 7 ] . The surgery includes standard surgical process craniotomy which removes a subdivision of skull to expose the encephalon underneath in order to unclutter the tumor. Besides, patients may choose to undergo optical maser microsurgery or supersonic aspiration to hold their tumors removed. 2 1 3 4 Figure 2 Craniotomy hypertext transfer protocol: //ebsco.smartimagebase.com/surgical-craniotomy/view-item? ItemID=40345 Accumulative Word Count: 242 Radiation Therapy Normally, radiation therapy ( RT ) is administered instantly after surgery. It works chiefly by damaging the Deoxyribonucleic acid of tumor cells, killing any residuary tumor cells after surgical remotion of the tumour [ 3-6,32 ] . A research has shown that the average endurance clip has increased from 17 hebdomads ( treated with conventional attention ) to 37.5 hebdomads when the GBM patients were treated with RT entirely while combination of BNCU ( carmustine ) and RT produced a 40.5 hebdomad average endurance [ 11 ] . Table 1 Randomized surveies of post-operative radiation compared with no radiation therapy in malignant gliomaa [ 23 ] Study [ Ref. ] Study group Radiation dose Gy/ no. of fraction No. of patients randomized ( analyzed ) Median endurance ( hebdomads ) Overall endurance P value Shapiro et al. , 1976 [ 62 ] Connecticut RT + CT – 60 16 ( 16 ) 17 ( 17 ) 30 44.5 NR Not important Andersen, 1978 [ 1 ] Surgery entirely RT – 45/25 57 ( 57 ) 51 ( 51 ) 15b 23b †¹0.005 Survival at 6 months Walker et al. , 1978 [ 78 ] vitamin D Surgery entirely RT – 50-60/25-35 42 ( 31 ) 93 ( 68 ) 14c 36c 0.001 Walker et al. , 1980 [ 79 ] vitamin D Connecticut RT – 60/30-35 111 ( 111 ) 118 ( 118 ) 31 37 0.003 Kristiansen et al. , 1981 [ 36 ] vitamin D Surgery entirely RT + / – Connecticut – 45/25 38 ( 38 ) 80 ( 80 ) 23 47 NR Significant Sandberg-Wollheim et al. , 1991 [ 60 ] Connecticut RT + CT – 58/27 87 ( 87 ) 84 ( 84 ) 42 62 0.028 a CT, chemotherapy ; NR, non reported ; RT, radiation therapy. B Calculated from survival curve. 500 Multi-arm survey that included a radiation plus chemotherapy arm. For both surveies by Walker et al. , merely information from the radiation entirely arm are shown in Table 2. Kristiansen et Al. reported combined informations from the radiation entirely arm and the radiation plus chemotherapy arm. In each of these surveies, there was a important survival benefit favouring radiation plus chemotherapy compared with no radiation therapy but no important difference in endurance between radiation entirely and radiation plus chemotherapy ( informations non shown ) . degree Celsiuss Merely consequences for the evaluable patients were reported ( 31 patients in the surgery entirely arm and 68 patients in the RT arm ) . Accumulative Word Count: 329 RT is normally administered through external beam radiation but internal radiation called Brachytherapy is besides possible. Each manner differs in how the radiation beginnings are delivered to the tumour [ 4-6,32 ] . Using IMRT ( Intensity-Modulated Radiation Therapy ) , a machine such as additive gas pedal delivers precise high-energy radiation doses ( eg: X raies ) to the tumor accurately and kills the affected cells [ 6,33 ] . Most patients will have the intervention for five to seven hebdomads [ 6,32,34 ] . Typically, around 6000 to 6500 units of radiation are delivered over seven hebdomads [ 6 ] . In contrast, brachytherapy topographic point the radiation beginnings every bit near as possible to the targeted cells in shorter clip comparison to external radiation. It consists of radioactive implants in the signifier of catheters or seeds which has impermanent radioactive beginnings in the tumor [ 8 ] . Figure 3 Brachythrapy hypertext transfer protocol: //ebsco.smartimagebase.com/brachytherapy/view-item? ItemID=24923 Besides, stereotactic radiosurgery, a noninvasive method of presenting an intense and focused dosage of radiation to a little country can be used for GBM excessively. Treatment dose is individualized but the typical dosage is about 2500 units of radiation per intervention [ 6 ] . Other signifiers of radiation intervention such as installing of inflatable balloon incorporating liquid radiation or interpolation of monoclonal antibodies tagged with radioactive substances may be used [ 8 ] . Accumulative Word Count: 519 Chemotherapy Chemotherapy may be given after surgical resection and radiation. In this therapy, chemotherapeutic drugs play an of import function in impacting retroflexing cells by damaging the Deoxyribonucleic acid of these cells. The most normally used drugs are carmustine ( BNCU ) , lomustine ( CCNU ) , temozolomide ( Temodar ) and procarbazine. They are classified as alkylating agents which are DNA-damaging drugs. These drugs alkylate the Deoxyribonucleic acid in the tumor cells, doing the dual strands to be cross-linked to each other in an inappropriate manner. This thereby, blocks DNA reproduction and bit by bit leads to cell decease [ 4,5,8 ] . Soon, Gliadel Wafer – a biodegradable wafer soaked with BNCU is prevailing among the interventions. This is done by engrafting wafers in the pit after surgical remotion of the tumor. The wafers so easy let go of high concentrations of BCNU straight into the tumour country over a period of 2-3 hebdomads. Gliadel does non supply a remedy for GBM but is believed to be capable of protracting endurance. Apart from that, temozolomide is more frequently administered orally on monthly rhythm for 6-12 months after surgery and radiation as a care therapy [ 6,8,28,29 ] . Traditional chemotherapy drugs can be effectual, but most of them do non separate between healthy and tumour cells, thereby forestalling the disposal of high doses to kill the unnatural cells. What is more, their generalised toxicity can do terrible side effects. Targeted therapy drugs like Avastin ( bevacizumab ) are more precise than some chemotherapy drugs and tend to hold fewer side effects. It has been approved by FDA in 2009 as a new biologic drug to handle GBM. Avastin acts chiefly as an angiogenesis inhibitors by decelerating the growing of new blood vass environing the tumor. It selectively blocks VEGF to suppress the activation of VEGF receptors tyrosine kinases VEGFR1 and VEGFR2 [ 13-15 ] . There are some surveies to turn out that approximately 20-30 % patients with GBM do react to the drugs [ 27 ] . Accumulative Word Count: 823 A Graph 1 Kaplan-Meier endurance curves for patients treated with steroids and ( A ) resective surgery merely, ( B ) resective surgery and radiation therapy and ( C ) resective surgery, radiation therapy and chemotherapy. [ 12 ] Bacillus C Accumulative Word Count: 848 Social and Economic Deductions The trouble to digest with the side effects of the medicines such as sleepiness and hair loss may do GBM patients to experience down and hurt. They may be easy frustrated by concerns they suffer often or experience suffering and hopeless after the diagnosing [ 34 ] . This could take to serious societal impact and would worry the people around them. Furthermore, most of the patients find it hard to return to work due to decrease in productiveness. A study has shown that with 91 % patients were employed before diagnosing, merely 33 % of them continue working after interventions. While health professionals who were still working experience employment alterations such as taking leave of absence to be with their loved 1s for interventions or taking on extra paid work might experience stressed and have to fight difficult to get by with the tough life [ 9 ] . In order to run a normal life, patients require undergo a plentifulness of interventions including hospitalization after surgery which would do great fiscal load. It is estimated that cost of GBM interventions ranged from ˆ10 893 to ˆ125 275 [ 22 ] . Trouble of obtaining insurance makes the status even worse. Drugs that are necessary for GBM interventions are expensive and are normally administered over long period of clip. All this becomes a beginning of depression which affects non merely the patients but their households and friends [ 9 ] . The return of GBM after conventional therapy is inevitable. This so creates unstoppable medical crisis every bit good as fiscal hurt to the patients and their households. Accumulative Word Count: 1084 Benefits and Hazards I believe a combination of surgery, radiation therapy and chemotherapy is the most effectual intervention for GBM presently. In malice of its forecast has remained hapless for the last few decennaries, patients do acquire better after adhering to this standard therapy. Although GBM can non be cured, the patients had have their survival clip prolonged, acquiring a opportunity to pass their last few months with their loved 1s in a meaningful manner [ 34 ] . Nevertheless, the interventions do enforce distressing side effects to human wellness. Despite killing tumour cells, alkylating agents used are considered toxic, ensuing in suppression or lowering of blood counts. They have been associated with important sickness, hair loss, weariness and sterility [ 5 ] . High doses of BNCU may take to damage and marking of the lungs while procarbazine can do raging concern, purging and numbness. Hence, doses of drugs administered have to be carefully monitored by doctor to avoid taking to unwanted effects. Recently invented drugs temozolomide, has comparatively mild side effects but they are still inevitable [ 6 ] . Meanwhile, hazard of developing acute leukaemia old ages subsequently is increased when patients are exposed to alkylating agents [ 5 ] . Avastin, a freshly developed drug, provides a more effectual therapy for GBM. However, it potentially creates fatal toxicity, doing the late closed surgical lesion interruptions down. Some claim that the development of toxicity by avastin may shorten endurance in some patients when it is added to radiotherapy and temozolomide. Thus, researches on the effectivity and safety of use of avastin should be carried on continually until desirable consequences are obtained [ 20 ] . In add-on, the return of the tumor is ineluctable, with the average endurance rate of patients who relapse runing from 3-6 months despite aggressive intervention [ 10 ] . Patients may develop the feeling that the medicines are useless or may give up because of the intolerable side effects and the unstoppable backsliding of disease. This will take to non-adherence to therapy and increase the hazard of mortality. However, in my sentiment, the multimodal treatments I discuss above are still considered the best solution for GBM as they outweigh the hazards by protracting the patients ‘ survival clip. Accumulative Word Count: 1432 Alternate Treatments Gene therapy Another promising attack of handling GBM is cistron therapy. Herpes simplex virus thymidine kinase/ganciclovir ( HSV-tk/GCV ) has evolved as a cytotoxic cistron therapy. In this instance, recombinant adenoviral vectors are used to give favorable consequences. Adenoviral HSV-tk ( AdHSV-tk ) is able to assail the residuary dividing tumour cells while go forthing the non-dividing nerve cells unharmed. What ‘s more, it can destruct the malignant neoplastic disease cells through bystander- consequence [ 19 ] . HSV-tk first converts GCV to GCV-monophosphate [ 16,17 ] . Then, cellular kinases farther convert this merchandise to GCV-triphosphate which is a hapless substrate for uninterrupted DNA elongation due to the lacking of 3 ‘ hydroxyl group that is needed to organize phosphodiester bond in chain-elongation-reaction. Ultimately, nonfunctional Deoxyribonucleic acid fragments are formed, triping programmed cell death in malignant neoplastic disease cells [ 18 ] . Nowadays, AdH SV-tk /GCV is going preferred comparisons to conventional radiation therapy and chemotherapy due to its fewer inauspicious effects. Figure 4 The rule of HSV-tk/GCV cistron therapy. hypertext transfer protocol: //www.gtmb.org/VOL4A/GTMBVOL4AHTML/23_Adachi_files/image001.gif Accumulative Word Count: 1575 Table 2 Surveies by Sandmair et Al. and Immonen et Al. demo a singular protraction of endurance in patients treated with AdHSV-tk [ 19 ] . Patients Vector Phase Gene Transfer Method Adverse Effectss Survival ( Months ) Response Brain Tumour Glioblastoma Multiforme Problem Health And Social Care Essay GBM normally affects people who older than 50 old ages old although the disease can happen in patients from all age group [ 2,25,28 ] . Patients suffer ictus, concern, ocular perturbation and sometimes personality alterations which can do great emotional hurt [ 25,30,31 ] . The average endurance of GBM patients is hapless, with about 12 to 14 months [ 7 ] . At this minute, the exact causes of GBM still remain vague to the scientists. Figure 1 GBM tumor is normally found in frontal and temporal lobe. Beginning: hypertext transfer protocol: //ebsco.smartimagebase.com/brain-tumor/view-item? ItemID=4027 Accumulative Word Count: 131 Possible Treatments Surgery Surgery is normally the initial measure to handle GBM by taking every bit much tumor as possible. It is non healing but aims to cut down the tumor ‘s size every bit much as possible so that other therapies right after the surgery can be more effectual. Furthermore, surgical resection Acts of the Apostless to alleviate hydrops by debulking tumor every bit good as being a alleviative intervention for neurologic symptoms such as ictus activity [ 7 ] . The surgery includes standard surgical process craniotomy which removes a subdivision of skull to expose the encephalon underneath in order to unclutter the tumor. Besides, patients may choose to undergo optical maser microsurgery or supersonic aspiration to hold their tumors removed. 2 1 3 4 Figure 2 Craniotomy hypertext transfer protocol: //ebsco.smartimagebase.com/surgical-craniotomy/view-item? ItemID=40345 Accumulative Word Count: 242 Radiation Therapy Normally, radiation therapy ( RT ) is administered instantly after surgery. It works chiefly by damaging the Deoxyribonucleic acid of tumor cells, killing any residuary tumor cells after surgical remotion of the tumour [ 3-6,32 ] . A research has shown that the average endurance clip has increased from 17 hebdomads ( treated with conventional attention ) to 37.5 hebdomads when the GBM patients were treated with RT entirely while combination of BNCU ( carmustine ) and RT produced a 40.5 hebdomad average endurance [ 11 ] . Table 1 Randomized surveies of post-operative radiation compared with no radiation therapy in malignant gliomaa [ 23 ] Study [ Ref. ] Study group Radiation dose Gy/ no. of fraction No. of patients randomized ( analyzed ) Median endurance ( hebdomads ) Overall endurance P value Shapiro et al. , 1976 [ 62 ] Connecticut RT + CT – 60 16 ( 16 ) 17 ( 17 ) 30 44.5 NR Not important Andersen, 1978 [ 1 ] Surgery entirely RT – 45/25 57 ( 57 ) 51 ( 51 ) 15b 23b †¹0.005 Survival at 6 months Walker et al. , 1978 [ 78 ] vitamin D Surgery entirely RT – 50-60/25-35 42 ( 31 ) 93 ( 68 ) 14c 36c 0.001 Walker et al. , 1980 [ 79 ] vitamin D Connecticut RT – 60/30-35 111 ( 111 ) 118 ( 118 ) 31 37 0.003 Kristiansen et al. , 1981 [ 36 ] vitamin D Surgery entirely RT + / – Connecticut – 45/25 38 ( 38 ) 80 ( 80 ) 23 47 NR Significant Sandberg-Wollheim et al. , 1991 [ 60 ] Connecticut RT + CT – 58/27 87 ( 87 ) 84 ( 84 ) 42 62 0.028 a CT, chemotherapy ; NR, non reported ; RT, radiation therapy. B Calculated from survival curve. 500 Multi-arm survey that included a radiation plus chemotherapy arm. For both surveies by Walker et al. , merely information from the radiation entirely arm are shown in Table 2. Kristiansen et Al. reported combined informations from the radiation entirely arm and the radiation plus chemotherapy arm. In each of these surveies, there was a important survival benefit favouring radiation plus chemotherapy compared with no radiation therapy but no important difference in endurance between radiation entirely and radiation plus chemotherapy ( informations non shown ) . degree Celsiuss Merely consequences for the evaluable patients were reported ( 31 patients in the surgery entirely arm and 68 patients in the RT arm ) . Accumulative Word Count: 329 RT is normally administered through external beam radiation but internal radiation called Brachytherapy is besides possible. Each manner differs in how the radiation beginnings are delivered to the tumour [ 4-6,32 ] . Using IMRT ( Intensity-Modulated Radiation Therapy ) , a machine such as additive gas pedal delivers precise high-energy radiation doses ( eg: X raies ) to the tumor accurately and kills the affected cells [ 6,33 ] . Most patients will have the intervention for five to seven hebdomads [ 6,32,34 ] . Typically, around 6000 to 6500 units of radiation are delivered over seven hebdomads [ 6 ] . In contrast, brachytherapy topographic point the radiation beginnings every bit near as possible to the targeted cells in shorter clip comparison to external radiation. It consists of radioactive implants in the signifier of catheters or seeds which has impermanent radioactive beginnings in the tumor [ 8 ] . Figure 3 Brachythrapy hypertext transfer protocol: //ebsco.smartimagebase.com/brachytherapy/view-item? ItemID=24923 Besides, stereotactic radiosurgery, a noninvasive method of presenting an intense and focused dosage of radiation to a little country can be used for GBM excessively. Treatment dose is individualized but the typical dosage is about 2500 units of radiation per intervention [ 6 ] . Other signifiers of radiation intervention such as installing of inflatable balloon incorporating liquid radiation or interpolation of monoclonal antibodies tagged with radioactive substances may be used [ 8 ] . Accumulative Word Count: 519 Chemotherapy Chemotherapy may be given after surgical resection and radiation. In this therapy, chemotherapeutic drugs play an of import function in impacting retroflexing cells by damaging the Deoxyribonucleic acid of these cells. The most normally used drugs are carmustine ( BNCU ) , lomustine ( CCNU ) , temozolomide ( Temodar ) and procarbazine. They are classified as alkylating agents which are DNA-damaging drugs. These drugs alkylate the Deoxyribonucleic acid in the tumor cells, doing the dual strands to be cross-linked to each other in an inappropriate manner. This thereby, blocks DNA reproduction and bit by bit leads to cell decease [ 4,5,8 ] . Soon, Gliadel Wafer – a biodegradable wafer soaked with BNCU is prevailing among the interventions. This is done by engrafting wafers in the pit after surgical remotion of the tumor. The wafers so easy let go of high concentrations of BCNU straight into the tumour country over a period of 2-3 hebdomads. Gliadel does non supply a remedy for GBM but is believed to be capable of protracting endurance. Apart from that, temozolomide is more frequently administered orally on monthly rhythm for 6-12 months after surgery and radiation as a care therapy [ 6,8,28,29 ] . Traditional chemotherapy drugs can be effectual, but most of them do non separate between healthy and tumour cells, thereby forestalling the disposal of high doses to kill the unnatural cells. What is more, their generalised toxicity can do terrible side effects. Targeted therapy drugs like Avastin ( bevacizumab ) are more precise than some chemotherapy drugs and tend to hold fewer side effects. It has been approved by FDA in 2009 as a new biologic drug to handle GBM. Avastin acts chiefly as an angiogenesis inhibitors by decelerating the growing of new blood vass environing the tumor. It selectively blocks VEGF to suppress the activation of VEGF receptors tyrosine kinases VEGFR1 and VEGFR2 [ 13-15 ] . There are some surveies to turn out that approximately 20-30 % patients with GBM do react to the drugs [ 27 ] . Accumulative Word Count: 823 A Graph 1 Kaplan-Meier endurance curves for patients treated with steroids and ( A ) resective surgery merely, ( B ) resective surgery and radiation therapy and ( C ) resective surgery, radiation therapy and chemotherapy. [ 12 ] Bacillus C Accumulative Word Count: 848 Social and Economic Deductions The trouble to digest with the side effects of the medicines such as sleepiness and hair loss may do GBM patients to experience down and hurt. They may be easy frustrated by concerns they suffer often or experience suffering and hopeless after the diagnosing [ 34 ] . This could take to serious societal impact and would worry the people around them. Furthermore, most of the patients find it hard to return to work due to decrease in productiveness. A study has shown that with 91 % patients were employed before diagnosing, merely 33 % of them continue working after interventions. While health professionals who were still working experience employment alterations such as taking leave of absence to be with their loved 1s for interventions or taking on extra paid work might experience stressed and have to fight difficult to get by with the tough life [ 9 ] . In order to run a normal life, patients require undergo a plentifulness of interventions including hospitalization after surgery which would do great fiscal load. It is estimated that cost of GBM interventions ranged from ˆ10 893 to ˆ125 275 [ 22 ] . Trouble of obtaining insurance makes the status even worse. Drugs that are necessary for GBM interventions are expensive and are normally administered over long period of clip. All this becomes a beginning of depression which affects non merely the patients but their households and friends [ 9 ] . The return of GBM after conventional therapy is inevitable. This so creates unstoppable medical crisis every bit good as fiscal hurt to the patients and their households. Accumulative Word Count: 1084 Benefits and Hazards I believe a combination of surgery, radiation therapy and chemotherapy is the most effectual intervention for GBM presently. In malice of its forecast has remained hapless for the last few decennaries, patients do acquire better after adhering to this standard therapy. Although GBM can non be cured, the patients had have their survival clip prolonged, acquiring a opportunity to pass their last few months with their loved 1s in a meaningful manner [ 34 ] . Nevertheless, the interventions do enforce distressing side effects to human wellness. Despite killing tumour cells, alkylating agents used are considered toxic, ensuing in suppression or lowering of blood counts. They have been associated with important sickness, hair loss, weariness and sterility [ 5 ] . High doses of BNCU may take to damage and marking of the lungs while procarbazine can do raging concern, purging and numbness. Hence, doses of drugs administered have to be carefully monitored by doctor to avoid taking to unwanted effects. Recently invented drugs temozolomide, has comparatively mild side effects but they are still inevitable [ 6 ] . Meanwhile, hazard of developing acute leukaemia old ages subsequently is increased when patients are exposed to alkylating agents [ 5 ] . Avastin, a freshly developed drug, provides a more effectual therapy for GBM. However, it potentially creates fatal toxicity, doing the late closed surgical lesion interruptions down. Some claim that the development of toxicity by avastin may shorten endurance in some patients when it is added to radiotherapy and temozolomide. Thus, researches on the effectivity and safety of use of avastin should be carried on continually until desirable consequences are obtained [ 20 ] . In add-on, the return of the tumor is ineluctable, with the average endurance rate of patients who relapse runing from 3-6 months despite aggressive intervention [ 10 ] . Patients may develop the feeling that the medicines are useless or may give up because of the intolerable side effects and the unstoppable backsliding of disease. This will take to non-adherence to therapy and increase the hazard of mortality. However, in my sentiment, the multimodal treatments I discuss above are still considered the best solution for GBM as they outweigh the hazards by protracting the patients ‘ survival clip. Accumulative Word Count: 1432 Alternate Treatments Gene therapy Another promising attack of handling GBM is cistron therapy. Herpes simplex virus thymidine kinase/ganciclovir ( HSV-tk/GCV ) has evolved as a cytotoxic cistron therapy. In this instance, recombinant adenoviral vectors are used to give favorable consequences. Adenoviral HSV-tk ( AdHSV-tk ) is able to assail the residuary dividing tumour cells while go forthing the non-dividing nerve cells unharmed. What ‘s more, it can destruct the malignant neoplastic disease cells through bystander- consequence [ 19 ] . HSV-tk first converts GCV to GCV-monophosphate [ 16,17 ] . Then, cellular kinases farther convert this merchandise to GCV-triphosphate which is a hapless substrate for uninterrupted DNA elongation due to the lacking of 3 ‘ hydroxyl group that is needed to organize phosphodiester bond in chain-elongation-reaction. Ultimately, nonfunctional Deoxyribonucleic acid fragments are formed, triping programmed cell death in malignant neoplastic disease cells [ 18 ] . Nowadays, AdH SV-tk /GCV is going preferred comparisons to conventional radiation therapy and chemotherapy due to its fewer inauspicious effects. Figure 4 The rule of HSV-tk/GCV cistron therapy. hypertext transfer protocol: //www.gtmb.org/VOL4A/GTMBVOL4AHTML/23_Adachi_files/image001.gif Accumulative Word Count: 1575 Table 2 Surveies by Sandmair et Al. and Immonen et Al. demo a singular protraction of endurance in patients treated with AdHSV-tk [ 19 ] . Patients Vector Phase Gene Transfer Method Adverse Effectss Survival ( Months ) Response